 Applications
Peptide libraries are cost-effective research tools for applications without the need for highly purified peptides. Peptides of the libraries can be synthesized with blocked or free terminal ends and additional modifications, if required. Free terminal ends are needed, for example, to represent sequences that are comparable to peptides originating from proteasomal processed proteins (e.g. MHC class I restricted peptides). Blocked N- and C-termini are commonly used to represent internal sequences of proteins or to increase the stability to exonucleases. INTAVIS can deliver peptide libraries appropriate for your particular application:
- overlapping peptides for B- and T-cell epitope mapping
- mapping of protein/protein interactions (ELISA or pull-down assays, e.g. by using magnetic beads)
- peptides as kinase substrates
- phosphorylated peptides as phosphatase substrates
- internally quenched peptides for protease assays (FRET)
- peptides with terminal biotin or desthiobiotin for attachment to streptavidin coated plates or beads
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